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Papers of the Week

2022 Dec 23

J Ethnopharmacol

Curcuminoids inhibit human and rat placental 3β-hydroxysteroid dehydrogenases: Structure-activity relationship and in silico docking analysis.


Sang J, Chu J, Zhao X, Quan H, Ji Z, Wang S, Tang Y, Hu Z, Li H, Li L, Ge R-S
J Ethnopharmacol. 2022 Dec 23:116051.
PMID: 36572324.


In traditional Chinese medicine, curcuma longa L has been applied to treat pain and tumour-related symptoms for over thousands of years. Curcuminoids, polyphenolic compounds, are the main pharmacological component from the rhizome of Curcuma longa L. Pharmacological investigations have found that curcuminoids have many pharmacological activities of anti-inflammatory, anti-tumour, and anti-metastasis.