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Papers of the Week

2022 Dec 23

BMC Gastroenterol



Anorectal manometry for the diagnosis of pelvic floor disorders in patients with hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome.


Zhou W, Zikos TA, Halawi H, Sheth VR, Gurland B, Nguyen LA, Neshatian L
BMC Gastroenterol. 2022 Dec 23; 22(1):538.
PMID: 36564719.


Functional gastrointestinal disorders (FGID) including impaired rectal evacuation are common in patients with Hypermobility Spectrum Disorder (HSD) or Hypermobile Ehlers-Danlos Syndrome (hEDS). The effect of connective tissue pathologies on pelvic floor function in HSD/hEDS remains unclear. We aimed to compare clinical characteristics and anorectal pressure profile in patients with HSD/hEDS to those of age and sex matched controls.