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Papers of the Week

2022 Dec 23

Infect Dis (Lond)

The presence of intraperitoneal, retroperitoneal and pleural fluid in acute Puumala hantavirus infection.


Tervo L, Outinen T, Kiekara T, Tietäväinen J, Paakkala A, Pörsti I, Huhtala H, Mäkelä S, Mustonen J
Infect Dis (Lond). 2022 Dec 23:1-9.
PMID: 36562294.


Puumala hantavirus (PUUV) causes most cases of haemorrhagic fever with renal syndrome (HFRS) in Europe. PUUV infection is characterised by acute kidney injury, thrombocytopenia and increased capillary leakage. Typical symptoms are fever, headache, nausea, abdominal and back pain. This study aimed to evaluate the amount and distribution of intraperitoneal, retroperitoneal and pleural fluid and the association of fluid collections to the symptoms and clinical findings in patients with acute PUUV infection.