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Papers of the Week

Papers: 17 Dec 2022 - 23 Dec 2022

2022 Aug-Dec

Neurobiol Pain


Comparison of Pain-Like behaviors in two surgical incision animal models in C57BL/6J mice.


Ulker E, Caillaud M, Koseli E, Contreras K, Alkhlaif Y, Lindley E, Barik M, Ghani S, Bryant CD, Imad Damaj M
Neurobiol Pain. 2022 Aug-Dec; 12:100103.
PMID: 36531613.


Management of pain post-surgery is crucial for tissue healing in both veterinary and human medicine. Overuse of some analgesics such as opioids may lead to addictions and worsen pain syndromes (opioid-induced hyperalgesia), while underuse of it may affect the welfare of the patient. Therefore, the importance of using surgery models in laboratory animals is increasing, with the goal of improving our understanding of pain neurobiology and developing safer analgesics.