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Papers of the Week

Papers: 17 Dec 2022 - 23 Dec 2022


Front Immunol


SFRP4IGFBP5 NKT cells induced neural-like cell differentiation to contribute to adenomyosis pain.


Chen Y, Zhu J, Chen L, Shen Y, Zhang J, Wang Q
Front Immunol. 2022; 13:945504.
PMID: 36532077.


Adenomyosis is an estrogen-dependent gynecological disease. The pathogenesis of chronic pain, the main clinical symptom of adenomyosis, remains undefined. As a combination lymphocyte with both T-cell and natural killer (NK)-cell properties, NK T (NKT) cells play a role in immune defense against numerous diseases and modulate cell differentiation.