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Papers of the Week

2022 Dec 16


A broad assessment of covid-19 vaccine safety using tree-based data-mining in the vaccine safety datalink.


Yih KW, Daley MF, Duffy J, Fireman B, McClure D, Nelson J, Qian L, Smith N, Vazquez-Benitez G, Weintraub E, Williams JTB, Xu S, Maro JC
Vaccine. 2022 Dec 16.
PMID: 36535825.


Except for spontaneous reporting systems, vaccine safety monitoring generally involves pre-specifying health outcomes and post-vaccination risk windows of concern. Instead, we used tree-based data-mining to look more broadly for possible adverse events after Pfizer-BioNTech, Moderna, and Janssen COVID-19 vaccination.