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Papers of the Week

2022 Dec 16

J Med Case Rep



Lessons learned from long-term side effects after zoledronic acid infusion following denosumab treatment: a case report and review of the literature.


Zoledronic acid is an intravenous, highly potent aminobisphosphonate for use in patients with primary or secondary osteoporosis. Zoledronic acid-induced prolonged side-effects are well known and quite common. However, severe side-effects can be a threat to life. We report a case of severe side-effects induced by zoledronic acid infusion, and its positive effect on long-term back pain.