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Papers of the Week

Papers: 10 Dec 2022 - 16 Dec 2022

Animal Studies

2022 Dec 12

J Transl Med



Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain.


Wu D, Zhang Y, Zhao C, Li Q, Zhang J, Han J, Xu Z, Li J, Ma Y, Wang P, Xu H
J Transl Med. 2022 Dec 12; 20(1):583.
PMID: 36503542.


Growing evidence shows that C-Type Lectin Domain Containing 7A (Clec7a) may be involved into neuroinflammatory injury of various neurological diseases. However, its roles in neuropathic pain remain unclear.