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Papers: 10 Dec 2022 - 16 Dec 2022

2022 Dec 12

BMC Musculoskelet Disord



Possible synergic action of non-steroidal anti-inflammatory drugs and glucosamine sulfate for the treatment of knee osteoarthritis: a scoping review.


Veronese N, Ecarnot F, Cheleschi S, Fioravanti A, Maggi S
BMC Musculoskelet Disord. 2022 Dec 12; 23(1):1084.
PMID: 36510167.


Several studies have reported that glucosamine sulfate (GS) can improve knee osteoarthritis (OA) symptomatology. In parallel, the disease-modifying effects of non-steroidal anti-inflammatory drugs (NSAIDs) in knee OA have also been investigated. However, limited literature has reported the combined effect of GS and NSAIDs. The aim of this scoping review is to describe the scope and volume of the literature investigating the potential benefits and synergistic effect of a combination of GS and NSAIDs in patients with knee OA.