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Papers of the Week


2022 Dec 02


Curr Top Med Chem

Phytochemistry and Polypharmacological potential of Colebrookea oppositifolia Sm.

Authors

Kumar D, Singla RK, Sharma P, Kumar L, Kaur N, Dhawan RK, Sharma S, Dua K, Sharma R
Curr Top Med Chem. 2022 Dec 02.
PMID: 36476430.

Abstract

Colebrookea oppositifolia Sm. is a valuable traditional therapeutic plant belonging to the family Lamiaceae. It is a dense and wool-like shrub that is mostly found in subtropical regions of some countries of Asia, such as China and India. It has been widely used for the mitigation of nervous system disorders like epilepsy. The active constituents of the plant have exhibited antioxidant, anti-microbial, and antifungal properties, which are considered due to the presence of polyphenols and flavonoids as chief chemical constituents. Flavonoids like quercetin, landenein, chrysin, and 5, 6, 7-trimethoxy flavones cause protein denaturation of the microbial cell wall.