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Papers of the Week

2022 Dec 08

BMC Infect Dis



End-user research in support of long-acting systemic antiretroviral delivery systems: insights from qualitative research with providers and target users in South Africa.


Brown MS, Hanif H, Little KM, Clark MR, Thurman AR, Flomen L, Doncel GF
BMC Infect Dis. 2022 Dec 08; 22(1):919.
PMID: 36482336.


While oral pre-exposure prophylaxis (PrEP) has been shown to reduce the risk of HIV, challenges such as adhering to a daily-dosing regimen and persistence have emerged as barriers for at-risks populations in South Africa. This qualitative research sought to investigate perceptions of and preferences for a long-acting, biodegradable implantable PrEP product designed to address these barriers.