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Papers of the Week

2022 Dec 09

Ear Nose Throat J

Survival Outcomes Associated With the Size of Opioid Prescriptions in the Management of Chronic Pain Related to Advanced Nasopharyngeal Carcinoma.


Li K, Zhang S, Sun W, Zhang Y, Yu M, Zhang G, Yu W
Ear Nose Throat J. 2022 Dec 09:1455613221145093.
PMID: 36482685.


Patients with advanced nasopharyngeal carcinoma (ANC) often experience chronic pain. Opioids are generally recommended to treat tumor-related pain, but increased opioid use may lead to detrimental aftereffects, particularly with respect to tumor progression, resulting in reduced quality of life and increased risk of death. Our objective was to investigate whether the high size of opioid prescriptions is associated with poor overall survival (OS) in patients with ANC.