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Papers of the Week

Papers: 3 Dec 2022 - 9 Dec 2022

2022 Dec 05

Mol Brain



Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping.


Pi C, Tang W, Li Z, Liu Y, Jing Q, Dai W, Wang T, Yang C, Yu S
Mol Brain. 2022 Dec 05; 15(1):99.
PMID: 36471383.


Cortical spreading depression (CSD) is an electrophysiological event underlying migraine aura. Traditional CSD models are invasive and often cause injuries. The aim of the study was to establish a minimally invasive optogenetic CSD model and identify the active networks after CSD using whole-brain activity mapping.