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Papers of the Week

Papers: 3 Dec 2022 - 9 Dec 2022

2022 Dec 02

J Headache Pain



Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study.


Yuan Z, Wang W, Zhang X, Bai X, Tang H, Mei Y, Zhang P, Qiu D, Zhang X, Zhang Y, Yu X, Sui B, Wang Y
J Headache Pain. 2022 Dec 02; 23(1):154.
PMID: 36460958.


The definitive pathogenic mechanisms underlying chronic migraine (CM) remain unclear. Mounting evidence from functional and structural magnetic resonance imaging (MRI) studies suggests that the caudate nucleus (CN) plays a role in the cognitive, sensory, and emotional integration of pain information in patients with migraine. However, evidence concerning the role played by CN in CM patients is limited. Here, we used the CN as the seed to explore patterns of functional connectivity (FC) among healthy controls (HCs), patients with episodic migraine (EM), and patients with CM.