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Papers of the Week

2022 Nov 25

Medicine (Baltimore)



Prophylactic antibiotics induce early postcraniotomy seizures in neurosurgery patients: A case series.


Lee N, Jee D-L, Kim H G
Medicine (Baltimore). 2022 Nov 25; 101(47):e31714.
PMID: 36451405.


Antibiotics can cause central nervous system disturbances, manifesting as dizziness, confusion, headache, and seizures. Seizures due to antibiotic administration are related to increased excitatory neurotransmission because antibiotics act as competitive antagonists of the γ-aminobutyric acid type A receptor.