I am a
Home I AM A Search Login

Papers of the Week

Papers: 26 Nov 2022 - 2 Dec 2022



Front Med (Lausanne)


The Institute of Physical Medicine and Rehabilitation, Hospital das Clínicas University of São Paulo School of Medicine comprehensive rehabilitation program for elderly people with knee osteoarthritis.


Imamura M, Shinzato GT, Sugawara AT, Saemy Tome Uchiyama S, Matheus D, Simis M, Ayres D V M, Dos Santos ACA, Assone T, Ramos V D, Fregni F, Battistella LR
Front Med (Lausanne). 2022; 9:1029140.
PMID: 36438035.


Knee osteoarthritis (OA) is a leading cause of disability in the elderly population. Chronic disabling pain is associated with maladaptive neuroplastic changes in brain networks, commonly associated with central sensitization. The main clinical features of nociplastic pain conditions include combined peripheral and central sensitization, and it is crucial to recognize this type of pain, as it responds to different therapies than nociceptive and neuropathic pain.