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Papers of the Week

2022 Dec

World Allergy Organ J



An update on the prevalence, chronicity, and severity of atopic dermatitis and the associated epidemiological risk factors in the Singapore/Malaysia Chinese young adult population: A detailed description of the Singapore/Malaysia Cross-Sectional Genetics


Lim J J, Lim Y Y E, Ng J Y, Malipeddi P, Ng Y T, Teo W Y, Wong Q Y A, Matta S A, Sio Y Y, Wong Y R, Teh K F, Rawanan Shah S M, Reginald K, Say Y-H, Chew F T
World Allergy Organ J. 2022 Dec; 15(12):100722.
PMID: 36438192.


Atopic Dermatitis (AD) is a highly pruritic, chronic-recurrent inflammatory skin condition associated with erythematous lesions that affect a significant proportion of the population. Although AD is a non-communicable disease, it can cause pain, unbearable itchiness, sleep disturbance, loss of work productivity, and reduced quality of life. As a heterogeneous disease, AD is influenced by multiple genes and environmental triggers. As such, it is imperative to gain a deeper insight into the intricate gene-environment relationship that results in the manifestation of AD.