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Papers of the Week

Papers: 26 Nov 2022 - 2 Dec 2022

Human Studies

2022 Nov 28

Eur J Pain

Molecular and clinical markers of pain relief in complex regional pain syndrome: An observational study.


Reinhold A K, Kindl G-K, Dietz C, Scheu N, Mehling K, Brack A, Birklein F, Rittner HL
Eur J Pain. 2022 Nov 28.
PMID: 36440973.


Complex regional pain syndrome (CRPS) is marked by disproportionate pain after trauma. While long-term outcome is crucial to patients, predictors or biomarkers of the course of pain or CRPS symptoms are still lacking. In particular, microRNAs, such as miR-223, decreased in CRPS, have been described only in cross-sectional studies.