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Papers of the Week

Papers: 26 Nov 2022 - 2 Dec 2022

Human Studies, Pharmacology/Drug Development

2022 Nov 25

Eur Neurol

An Association Study of ESR1-XbaI and PvuII Gene Polymorphism in Migraine Susceptibility in the Jammu Region.


Kumar S, Raina J K, Sudershan A, Mahajan K, Jasrotia R, Maharana C, Panjalia RK, Kumar P
Eur Neurol. 2022 Nov 25:1-8.
PMID: 36436502.


Migraine is a neurovascular disorder and is clinically characterized by episodic attacks of mild to severe headaches. Due to the involvement of multiple environmental and genetic factors, it has become a much more complex neurological condition to understand. Apart from the environmental variables, a plethora of genes have been implicated, and one such example is ESR1. The present study was focused to find out the association of two important polymorphisms, namely, PvuII and XbaI of the ESR1 with migraine in the population of Jammu and Kashmir (UT).