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Papers of the Week


Papers: 26 Nov 2022 - 2 Dec 2022


Human Studies, Pharmacology/Drug Development


2022 Nov 25


Eur Neurol

An Association Study of ESR1-XbaI and PvuII Gene Polymorphism in Migraine Susceptibility in the Jammu Region.

Authors

Kumar S, Raina J K, Sudershan A, Mahajan K, Jasrotia R, Maharana C, Panjalia RK, Kumar P
Eur Neurol. 2022 Nov 25:1-8.
PMID: 36436502.

Abstract

Migraine is a neurovascular disorder and is clinically characterized by episodic attacks of mild to severe headaches. Due to the involvement of multiple environmental and genetic factors, it has become a much more complex neurological condition to understand. Apart from the environmental variables, a plethora of genes have been implicated, and one such example is ESR1. The present study was focused to find out the association of two important polymorphisms, namely, PvuII and XbaI of the ESR1 with migraine in the population of Jammu and Kashmir (UT).