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Papers of the Week


2022 Nov 26


Diabetes Obes Metab

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of danuglipron (PF-06882961), an oral small-molecule glucagon-like peptide-1 receptor agonist, in Japanese adults with type 2 diabetes mellitus.

Abstract

This study investigated the safety, tolerability, pharmacokinetics, and pharmacodynamics of danuglipron (PF-06882961)-a novel, oral, small-molecule glucagon-like peptide-1 receptor agonist-in Japanese participants with type 2 diabetes mellitus (T2DM).