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Papers of the Week

2022 Nov 24

Arch Gynecol Obstet

Evaluation of safety and effectiveness of gestrinone in the treatment of endometriosis: a systematic review and meta-analysis.


de Souza Pinto L P, Ferrari G, Dos Santos I K, de Mello Roesler C R, de Mello Gindri I
Arch Gynecol Obstet. 2022 Nov 24.
PMID: 36434439.


Endometriosis is a common chronic gynecological disease defined as the presence of endometrial glands and stroma tissue outside the uterus. Gestrinone is an effective antiestrogen that induces endometrial atrophy and/or amenorrhea. The purpose of this systematic review is to provide an evaluation of safety and effectiveness of gestrinone for the treatment of endometriosis.