I am a
Home I AM A Search Login

Papers of the Week

2022 Nov 23

BMC Pulm Med



Retrospective review comparing intrapleural fibrinolytic therapy (alteplase) and surgical intervention in complex pleural effusion.


Abdul Hamid M F, Hasbullah A H H, Mohamad Jailaini M F, Nik Abeed N N, Ng B H, Haron H, Md Ali N A, Ismail M I, Nik Ismail N A, Abdul Rahman M R, Ban A Y-L
BMC Pulm Med. 2022 Nov 23; 22(1):439.
PMID: 36419155.


Intrapleural fibrinolytic therapy (IPFT) is one of the treatment options for complex pleural effusion. In this study, the IPFT agent used was alteplase, a tissue plasminogen activator (t-PA). This study aims to determine the difference in the outcome of patients with complex pleural effusion between IPFT and surgery in terms of radiological improvement, inflammatory parameters, length of stay, and post-intervention complications.