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Papers of the Week


2022 Nov 23


BMC Pulm Med


22


1

Retrospective review comparing intrapleural fibrinolytic therapy (alteplase) and surgical intervention in complex pleural effusion.

Authors

Abdul Hamid M F, Hasbullah A H H, Mohamad Jailaini M F, Nik Abeed N N, Ng B H, Haron H, Md Ali N A, Ismail M I, Nik Ismail N A, Abdul Rahman M R, Ban A Y-L
BMC Pulm Med. 2022 Nov 23; 22(1):439.
PMID: 36419155.

Abstract

Intrapleural fibrinolytic therapy (IPFT) is one of the treatment options for complex pleural effusion. In this study, the IPFT agent used was alteplase, a tissue plasminogen activator (t-PA). This study aims to determine the difference in the outcome of patients with complex pleural effusion between IPFT and surgery in terms of radiological improvement, inflammatory parameters, length of stay, and post-intervention complications.