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Papers of the Week


2022 Nov 25


J Clin Lab Anal

The roles and mechanisms of circular RNAs related to mTOR in cancers.

Authors

Cao C, Wang Y, Wu X, Li Z, Guo J, Sun W
J Clin Lab Anal. 2022 Nov 25:e24783.
PMID: 36426933.

Abstract

Circular RNAs (circRNAs) are stable molecules with covalently closed structures that have an irreplaceable role in the occurrence, progression, and even treatment of plenty of cancers. Mammalian/mechanistic target of rapamycin (mTOR) is a key regulator in cancers and plays several biological functions, such as proliferation, migration, invasion, autophagy, and apoptosis.