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Papers of the Week

Papers: 26 Nov 2022 - 2 Dec 2022


2022 Nov 25

Curr Med Res Opin

Appropriate use of tapentadol: focus on the optimal tapering strategy.


Vellucci R, Fornasari D
Curr Med Res Opin. 2022 Nov 25:1-7.
PMID: 36427080.


Due to its opioid and non-opioid mechanism of action, tapentadol is considered an atypical opioid with improved gastrointestinal tolerability versus traditional opioids. As for all opioid analgesics it is important to understand how to discontinue a treatment when it is not needed anymore. The aim of this article was to provide an overview of opioid therapy in non-cancer pain, with a specific focus on tapering of tapentadol in patients with chronic non-cancer pain, and suggestions on how to achieve tapering.