I am a
Home I AM A Search Login

Papers of the Week

Papers: 19 Nov 2022 - 25 Nov 2022

2022 Nov 22

Pain Ther

Effectiveness and Safety of Chronic Migraine Preventive Treatments: A Systematic Literature Review.


Blumenfeld AM, Kaur G, Mahajan A, Shukla H, Sommer K, Tung A, Knievel KL
Pain Ther. 2022 Nov 22.
PMID: 36417165.


Numerous medications are used for the preventive treatment of chronic migraine (CM), including oral treatments, onabotulinumtoxinA (onabotA; BOTOX), and calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs). Despite substantial clinical trial evidence, less is published about the real-world experience of these treatments based on data routinely collected from a variety of sources. This systematic review assessed real-world evidence on the effectiveness and safety of preventive treatments for CM in adults.