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Papers of the Week

Papers: 19 Nov 2022 - 25 Nov 2022

2022 Oct 31


Acute pancreatitis precedes chronic pancreatitis in the majority of patients: Results from the NAPS2 consortium.


Singh VK, Whitcomb DC, Banks PA, Alkaade S, Anderson MA, Amann ST, Brand RE, Conwell DL, Cote GA, Gardner TB, Gelrud A, Guda N, Forsmark CE, Lewis M, Sherman S, Muniraj T, Romagnuolo J, Tan X, Tang G, Sandhu BS, et al.
Pancreatology. 2022 Oct 31.
PMID: 36404201.


The mechanistic definition of chronic pancreatitis (CP) identifies acute pancreatitis (AP) as a precursor stage. We hypothesized that clinical AP frequently precedes the diagnosis of CP and is associated with patient- and disease-related factors. We describe the prevalence, temporal relationship and associations of AP in a well-defined North American cohort.