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Papers of the Week

2022 Nov

Skin Appendage Disord



Nail Loss in Mild to Moderate Pemphigus Vulgaris.


Vander Does A, Gamret A C, Yosipovitch G
Skin Appendage Disord. 2022 Nov; 8(6):504-507.
PMID: 36407650.


Symptoms of pemphigus vulgaris (PV) rarely include nail findings. When ungual involvement does occur, the most common manifestations are paronychia and onychomadesis. Onycholysis is very uncommon, and complete nail loss has not been reported in the literature. Ungual involvement is thought to be closely correlated with disease severity, with only severe PV cases demonstrating nail symptoms.