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Papers of the Week

Papers: 19 Nov 2022 - 25 Nov 2022

2023 Jan

Vet Clin North Am Exot Anim Pract



Treatment of Pain in Rats, Mice, and Prairie Dogs.


Oates R, Tarbert DK
Vet Clin North Am Exot Anim Pract. 2023 Jan; 26(1):151-174.
PMID: 36402479.


Recent myomorph and scuiromorph rodent analgesia studies are reviewed and evaluated for potential clinical application. Differences between laboratory animal studies and clinical use in diseased animals are discussed. Analgesia classes reviewed include local anesthetics, nonsteroidal anti-inflammatories, acetaminophen, opioids, and adjuvants such as anticonvulsants. Routes of administration including sustained-release mechanisms are discussed, as are reversal agents. Drug interactions are reviewed in the context of beneficial multimodal analgesia as well as potential adverse effects. Dosage recommendations for clinical patients are explored.