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Papers of the Week

2022 Oct 28

Clin Neurol Neurosurg


Effective treatment of high-voltage pulsed radiofrequency combined with oxygen-ozone injection in acute zoster neuralgia.


Li L-M, Zhang Z-L, Zheng B-S, Jia L-L, Yu W-L, Du H-Y
Clin Neurol Neurosurg. 2022 Oct 28; 223:107496.
PMID: 36334554.


Postherpetic neuralgia (PHN) is the most common and severe complication of acute herpes zoster. Early treatment of herpes zoster neuralgia is of great significance to reduce the incidence of PHN. This retrospective study evaluated the efficacy and safety of the combination of high-voltage pulsed radiofrequency (PRF) and oxygen-ozone(O-O) injection in patients with acute zoster neuralgia (AZN) who failed to respond to conservative treatment.