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Papers of the Week


2022 Nov 03


BMJ Case Rep


15


11

Complete ophthalmoplegia diagnosed as Tolosa-Hunt syndrome on interval MRI.

Authors

Bowman S, Helming A
BMJ Case Rep. 2022 Nov 03; 15(11).
PMID: 36328364.

Abstract

Tolosa-Hunt syndrome is a rare cause of painful ophthalmoplegia, most commonly presenting with retro-orbital pain and eye motor nerve palsy, most often affecting a single eye. The condition is characterised by an idiopathic process causing granulomatous inflammation to the cavernous sinus affecting, one or multiple cranial nerves that pass therein. The mechanism underlying the inflammation is not well understood, but patients have been observed to respond to steroids during a flare. We present this as a unique case where a multidisciplinary team diagnosed Tolosa-Hunt syndrome despite non-specific MRI findings in the cavernous sinus 1 day following an initially normal MRI.