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Papers of the Week

Papers: 5 Nov 2022 - 11 Nov 2022

Human Studies


2022 Nov 04

J Eur Acad Dermatol Venereol

Validity and reliability of the Rosacea Area and Severity Index (RASI): A scoring system for clinical assessment of rosacea severity.


Wienholtz N, Thyssen JP, Christensen CE, Thomsen SF, Karmisholt KE, Jemec GBE, Lomholt HB, Heidenheim M, Simonsen AB, Sand C, Vestergaard C, Kaur-Knudsen D, Ammitzbøll E, Lørup E, Danielsen AG, Strauss G, Skov L, Andersen PH, Hald M, Idorn LW, et al.
J Eur Acad Dermatol Venereol. 2022 Nov 04.
PMID: 36331365.


Rosacea is a common chronic inflammatory facial skin disorder. Standardized evaluation of the severity and extent of rosacea is important for baseline assessment and treatment effect. The currently used Investigator's Global Assessment (IGA) is unspecific and fails to consider subtypes/phenotypes of rosacea and area involvement. The Rosacea Area and Severity Index (RASI) was developed to give a more nuanced evaluation of rosacea features in four facial skin areas adjusted to the relative importance of each area of the face to obtain an overall severity score.