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Papers of the Week

2022 Nov 04

Mol Biol Rep

NFK prevent postoperative abdominal adhesion through downregulating the TGF-β1 signaling pathway.


Zhao X, Piao X, Liu B, Xie R, Zhan T, Liang M, Tian J, Wang R, Chen C, Zhu J, Zhang Y, Yang B
Mol Biol Rep. 2022 Nov 04.
PMID: 36331752.


Postoperative abdominal adhesions (PAAs) represent a frequent condition occurring in more than 90% of patients undergoing abdomen and pelvic surgeries, which can cause chronic abdominal pain, female infertility, and repeated bowel obstruction, requiring repetitive surgical interventions causing morbidity and mortality, as well as high costs. It is therefore of paramount clinical importance and significance to develop practical and reliable strategies for preventing the occurrence of PAAs.