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Papers of the Week

Papers: 29 Oct 2022 - 4 Nov 2022

Human Studies

2021 Jun

Biol Psychiatry Glob Open Sci



Corticolimbic Circuitry in Chronic Pain Tracks Pain Intensity Relief Following Exposure In Vivo.


Timmers I, van de Ven VG, Vlaeyen J W, Smeets R J, Verbunt JA, de Jong JR, Kaas AL
Biol Psychiatry Glob Open Sci. 2021 Jun; 1(1):28-36.
PMID: 36324433.


A subset of patients with chronic pain who receive exposure in vivo (EXP) treatment experience clinically relevant relief of pain intensity. Although pain relief is not an explicit therapeutic target, it is important to understand how and why this concomitant effect occurs in some patients but not others. This longitudinal study therefore aimed to characterize brain plasticity as well as to explore pretreatment factors related to pain relief.