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Papers of the Week

Papers: 29 Oct 2022 - 4 Nov 2022

2022 Aug

Semin Neurol



Recent Advances and Updates in Trigeminal Autonomic Cephalalgias.


Wei DY, Goadsby PJ
Semin Neurol. 2022 Aug; 42(4):474-478.
PMID: 36323300.


Trigeminal autonomic cephalalgias (TACs) are discrete primary headache disorders, characterized by severe unilateral head pain, typically trigeminal distribution, with ipsilateral cranial autonomic symptoms. The conditions within this group are hemicrania continua, cluster headache, paroxysmal hemicrania, and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing and short-lasting unilateral neuralgiform headache with autonomic symptoms. Several advances have been made in understanding the pathogenesis and evolving treatment options in TACs. This review will outline the advances and updates in each TAC.