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Papers of the Week


2022 Oct 29


Ann Pharmacother

Naloxone Versus Methylnaltrexone for Opioid-Induced Constipation in Critically Ill Patients.

Authors

Habeeb EA, Tran LK, Goodberlet MZ, Lupi KE, DeGrado JR, Dube KM
Ann Pharmacother. 2022 Oct 29:10600280221132851.
PMID: 36314271.

Abstract

Opioid-induced constipation (OIC) may occur in up to 81% of critically ill patients and can lead to many complications. Opioid antagonists are a reasonable approach and may be used for managing OIC.