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Papers of the Week


2022 Oct 30


Cancer

Phase 1/2 study of epacadostat in combination with durvalumab in patients with metastatic solid tumors.

Authors

Naing A, Algazi AP, Falchook GS, Creelan BC, Powderly J, Rosen S, Barve M, Mettu NB, Triozzi PL, Hamm J, Zhou G, Walker C, Dong Z, Patel MR
Cancer. 2022 Oct 30.
PMID: 36309837.

Abstract

Targeting programmed cell death protein 1 (PD-1) and indoleamine 2,3-dioxygenase (IDO1) pathways is an appealing option for cancer treatment.