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Papers of the Week

2022 Oct 30


Phase 1/2 study of epacadostat in combination with durvalumab in patients with metastatic solid tumors.


Naing A, Algazi AP, Falchook GS, Creelan BC, Powderly J, Rosen S, Barve M, Mettu NB, Triozzi PL, Hamm J, Zhou G, Walker C, Dong Z, Patel MR
Cancer. 2022 Oct 30.
PMID: 36309837.


Targeting programmed cell death protein 1 (PD-1) and indoleamine 2,3-dioxygenase (IDO1) pathways is an appealing option for cancer treatment.