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Papers of the Week
Acetaminophen changes the RNA mA levels and mA-related proteins expression in IL-1β-treated chondrocyte cells.
Abstract
Acetaminophen is commonly recommended for the early analgesia of osteoarthritis. However, the molecular mechanism by which it acts remains unknown. The aim of this study is to investigate the effect of acetaminophen on inflammation and extracellular matrix degradation in human chondrocytes, and the possible molecular mechanisms involved in its effect.