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Papers of the Week

2022 Nov

Anticancer Res



Interleukin-18 (IL-18) Cytokine Serum Concentrations Correlate With Pain Scores and the Number of Analgesic Doses Following Surgery.


Eskelinen M, Saimanen I, Selander T, Holopainen A, Aspinen S, Hämäläinen E, Eskelinen M
Anticancer Res. 2022 Nov; 42(11):5521-5526.
PMID: 36288883.


Anti- and proinflammatory cytokines and plasma high-sensitivity C-reactive protein (hs-CRP) are used to assess inflammatory stress response (ISR) following surgery. However, the serum IL-18 (interleukin-18) cytokine values versus numeric rating scale (NRS) pain score and number of analgesic doses (NAD) postoperatively are unknown.