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Papers of the Week


2023 Jan


Neurol Neuroimmunol Neuroinflamm


10


1

Early-Stage Contactin-Associated Protein-like 2 Limbic Encephalitis: Clues for Diagnosis.

Authors

Benoit J, Muñiz-Castrillo S, Vogrig A, Farina A, Pinto A-L, Picard G, Rogemond V, Guery D, Alentorn A, Psimaras D, Rheims S, Honnorat J, Joubert B
Neurol Neuroimmunol Neuroinflamm. 2023 Jan; 10(1).
PMID: 36288995.

Abstract

Previous studies suggested that autoimmune limbic encephalitis with antibodies against contactin-associated protein-like 2 (CASPR2-encephalitis) is clinically heterogeneous and progresses slowly, preventing its early recognition. We aimed to describe the onset and progression of CASPR2-encephalitis and to assess long-term outcomes.