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Papers of the Week

2022 Oct 24

BMC Anesthesiol



The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.


Tochie J N, Bengono Bengono R S, Metogo J M, Ndikontar R, Ngouatna S, Ntock F N, Minkande J Z
BMC Anesthesiol. 2022 Oct 24; 22(1):325.
PMID: 36280804.


There is scarce data on the safety and efficacy of opioid-free anesthesia (OFA), in resource-limited settings due to the non-availability of dexmedetomidine, the reference OFA agent. We aimed to demonstrate the feasibility, efficacy and safety of a practical OFA protocol not containing dexmedetomidine, adapted for low-resource environments in very painful surgeries like gynecological surgery.