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Papers of the Week


2022 Oct 24


Trials


23


1

Clinical impact of cardiac magnetic resonance in patients with suspected coronary artery disease associated with chronic kidney disease (AQUAMARINE-CKD study): study protocol for a randomized controlled trial.

Authors

Noguchi T, Ota H, Matsumoto N, Morita Y, Oshita A, Kawasaki E, Kawasaki T, Moriwaki K, Kato S, Fukui K, Hoshi T, Watabe H, Kanaya T, Asaumi Y, Kataoka Y, Otsuka F, Takagi K, Yoneda S, Sawada K, Iwai T, et al.
Trials. 2022 Oct 24; 23(1):904.
PMID: 36280852.

Abstract

Although screening for coronary artery disease (CAD) using computed tomography coronary angiography in patients with stable chest pain has been reported to be beneficial, patients with chronic kidney disease (CKD) might have limited benefit due to complications of contrast agent nephropathy and decreased diagnostic accuracy as a result of coronary artery calcifications. Cardiac magnetic resonance (CMR) has emerged as a novel imaging modality for detecting coronary stenosis and high-risk coronary plaques without contrast media that is not affected by coronary artery calcification. However, the clinical use of this technology has not been robustly evaluated.