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Papers of the Week

2022 Oct 21

Medicine (Baltimore)



Exploratory analyses of biomarkers in blood and stratum corneum in patients with atopic dermatitis.


Maruyama A, Tamagawa-Mineoka R, Nishigaki H, Masuda K, Katoh N
Medicine (Baltimore). 2022 Oct 21; 101(42):e31267.
PMID: 36281133.


The pathogenesis of atopic dermatitis (AD) involves various mediators, including cytokines and chemokines, which are produced by immune cells, such as dendritic cells and lymphocytes, and non-immune cells, such as epidermal cells. Several mediators, including thymus and activation-regulated chemokine (TARC), are used as biomarkers for AD severity and activity. However, additional local and systemic biomarkers of AD are required.