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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Safety and immunogenicity of an Ad26.ZEBOV booster dose in children previously vaccinated with the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen: an open-label, non-randomised, phase 2 trial.

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2022 Oct 20


Lancet Infect Dis


http://www.ncbi.nlm.nih.gov/pubmed/36273490?dopt=Abstract

Safety and immunogenicity of an Ad26.ZEBOV booster dose in children previously vaccinated with the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen: an open-label, non-randomised, phase 2 trial.

Authors

Safety and immunogenicity of an Ad26.ZEBOV booster dose in children previously vaccinated with the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen: an open-label, non-randomised, phase 2 trial.
Manno D, Bangura A, Baiden F, Kamara A B, Ayieko P, Kallon J, Foster J, Conteh M, Connor N E, Koroma B, Njie Y, Borboh P, Keshinro B, Lawal B J, Kroma M T, Otieno G T, Deen A T, Choi E M-L, Balami A D, Gaddah A, et al.
Lancet Infect Dis. 2022 Oct 20.
PMID: 36273490.

Abstract

Children account for a substantial proportion of cases and deaths during Ebola virus disease outbreaks. We aimed to evaluate the safety and immunogenicity of a booster dose of the Ad26.ZEBOV vaccine in children who had been vaccinated with a two-dose regimen comprising Ad26.ZEBOV as dose one and MVA-BN-Filo as dose two.
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