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Papers of the Week

2022 Oct 24

Pain Pract

Second-degree burn induced by high-concentration topical capsaicin with mobility sequelae: a case report.


Trin K, Perino J, Allouchery M, Géniaux H, Miremont G, Salvo F
Pain Pract. 2022 Oct 24.
PMID: 36278478.


High-concentration topical capsaicin is used as a second line treatment for neuropathic pain. Transient, mild burning sensation and erythema are expected adverse drug reactions. Here, we report the first case of second degree burn after the application of a high-concentration topical capsaicin patch with secondary mobility sequelae. Nine months after the application, neuropathic pain still remained and the patient described mobility difficulties in daily activities, preventing her from returning to work. This report aims to raise the question of the benefit/risk ratio of high concentration topical capsaicin.