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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Two Phase 3, Randomized, Controlled Trials of Ruxolitinib Cream for Vitiligo.

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2022 Oct 20


N Engl J Med


http://www.ncbi.nlm.nih.gov/pubmed/36260792?dopt=Abstract


387


16

Two Phase 3, Randomized, Controlled Trials of Ruxolitinib Cream for Vitiligo.

Authors

Two Phase 3, Randomized, Controlled Trials of Ruxolitinib Cream for Vitiligo.
Rosmarin D, Passeron T, Pandya AG, Grimes P, Harris JE, Desai SR, Lebwohl M, Ruer-Mulard M, Seneschal J, Wolkerstorfer A, Kornacki D, Sun K, Butler K, Ezzedine K
N Engl J Med. 2022 Oct 20; 387(16):1445-1455.
PMID: 36260792.

Abstract

Vitiligo is a chronic autoimmune disease that causes skin depigmentation. A cream formulation of ruxolitinib (an inhibitor of Janus kinase 1 and 2) resulted in repigmentation in a phase 2 trial involving adults with vitiligo.
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