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Papers of the Week


2022 Oct 20


NMR Biomed

Ultrashort Echo Time MR Imaging of Osteochondral Junction.

Authors

Lombardi AF, Guma M, Chung CB, Chang EY, Du J, Ma Y-J
NMR Biomed. 2022 Oct 20:e4843.
PMID: 36264245.

Abstract

Osteoarthritis is a common chronic degenerative disease that causes pain and disability with increasing incidence worldwide. The osteochondral junction is a dynamic region of the joint that is associated with the early development and progression of osteoarthritis. Despite the substantial advances achieved in the imaging of cartilage and application to osteoarthritis in recent years, the osteochondral junction has received limited attention. This is primarily related to technical limitations encountered with conventional MR sequences that are relatively insensitive to short T2 tissues and the rapid signal decay that characterizes these tissues. MR sequences with ultra-short echo time (UTE) are of great interest since they can provide images of high resolution and contrast in this region. Here we briefly review the anatomy and function of cartilage, focusing on the osteochondral junction. We also review basic concepts and recent applications of UTE MR sequences focusing on the osteochondral junction.