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Papers of the Week


Papers: 15 Oct 2022 - 21 Oct 2022


Human Studies


2022 Oct


Health Technol Assess


26


39

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT.

Authors

Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R, Alam U, Julious SA, Cooper C, Loban A, Sutherland K, Glover R, Waterhouse S, Turton E, Horspool M, Gandhi R, et al.
Health Technol Assess. 2022 Oct; 26(39):1-100.
PMID: 36259684.

Abstract

The mainstay of treatment for diabetic peripheral neuropathic pain is pharmacotherapy, but the current National Institute for Health and Care Excellence guideline is not based on robust evidence, as the treatments and their combinations have not been directly compared.