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Papers of the Week

2022 Sep 26

J Clin Med



Silodosin Improves Pain and Urinary Frequency in Bladder Pain Syndrome/Interstitial Cystitis Patients.


Abreu-Mendes P, Araújo-Silva B, Charrua A, Cruz F, Pinto R
J Clin Med. 2022 Sep 26; 11(19).
PMID: 36233527.


Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC) is a bladder-related chronic inflammatory disease. Data indicate that stress enhances the excitability of bladder nociceptors through the stimulation of alpha1A-adrenoceptors. Stress is known to play a crucial role in BPS/IC patients. We aimed to assess the efficacy and safety of daily silodosin in refractory BPS/IC female patients and its correlation with stress coping.