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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.

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2022


J Inflamm Res


http://www.ncbi.nlm.nih.gov/pubmed/36238766?dopt=Abstract


15

Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.

Authors

Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.
Li B, Yang X, Zhang P, Guo J, Rong K, Wang X, Cao X, Zhou T, Zhao J
J Inflamm Res. 2022; 15:5767-5783.
PMID: 36238766.

Abstract

Low back pain (LBP) induced by intervertebral disc degeneration (IDD) brings progressively painful status and impairs the normal daily living. Engeletin is a plant-derived medicine with anti-inflammation and antioxidant functions. Therefore, we aim to confirm its protective effects against the intervertebral disc degeneration in vivo and in vitro.
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